16 April 2020

Japan’s Fujifilm has expanded manufacturing capacity to boost production of its influenza drug Avigan that is being assessed to potentially treat Covid-19. Fujifilm estimates to increase the production up to 100,000 treatment courses by July 2020 and then to 300,000 treatment courses by September.

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Roivant Sciences has dosed the first participant in the BREATHE clinical trial of monoclonal antibody gimsilumab to treat Covid-19 patients with lung injury or acute respiratory distress syndrome. Dosing occurred at Temple University Hospital, Philadelphia, but the trial will also be conducted at other sites.

Gilead Sciences has suspended a clinical trial assessing remdesivir for Covid-19 treatment in China due to lack of eligible patients. In the US government-run ClinicalTrials.gov website, the company updated the trial’s status as ‘Suspended (the epidemic of COVID-19 has been controlled well at present, no eligible patients can be recruitted.)’

Vanda Pharmaceuticals has partnered with Northwell Health to conduct a Phase III clinical trial of NK-1R antagonist tradipitant to treat severe Covid-19 pneumonia. Tradipitant is also currently in clinical development for gastroparesis, motion sickness and atopic dermatitis.

A vaccine candidate developed in China to protect from Covid-19 infection has entered Phase II clinical trial, reported Xinhua news agency citing a Ministry of Science and Technology official. The vaccine candidate, which has been created by a research firm affiliated to the Institute of Military Medicine under the Academy of Military Sciences, is said to have completed Phase I last month.

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