Health Canada has granted approval to amend the Canadian Treatments for COVID-19 (CATCO) trial protocol to incorporate Arch Biopartners’ lead drug candidate, LSALT Peptide (LSALT and Metablok), in a new dosing arm.

A No Objection Letter was issued by the Canadian regulatory authority to the trial team for the Clinical Trial Application – Amendment.

Related Company Profiles

View all

LSALT is a new drug candidate that acts on the acute organ inflammation in the lungs, liver and kidneys associated with various indications, including moderate to severe Covid-19 cases, irrespective of the variant.

The company noted that the dosing of subjects with LSALT peptide is anticipated to commence after obtaining final domestic approval and preparing the study site.

Being carried out at up to 55 hospitals in Canada, the multicentre, randomised, adaptive, controlled, open-label trial will identify new therapies for Covid-19 associated complications in patients. 

Funded by the Canadian Institutes of Health Research, the trial is supported by the Canadian Network of COVID-19 Clinical Trials Networks.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

Furthermore, Sunnybrook Research Institute (SRI) is serving as the trial sponsor and manages CATCO across all study centres in the country. 

SRI and Arch Biopartners signed a partnership agreement under which the former can use LSALT in a new trial arm. 

Arch Biopartners will deliver LSALT drug vials needed for dosing up to 350 subjects in the trial.

In January, the company obtained approval from the Research Ethics Board at the SRI to amend the trial protocol to include LSALT in a new arm of the CATCO. 

Focused on developing novel technologies, Arch Biopartners has a pipeline of new drug candidates that hinder lung, liver and kidney inflammation through the dipeptidase-1 (DPEP-1) pathway.

In March 2021, Arch Biopartners obtained approval to make some amendments to the protocol of the Phase II trial analysing LSALT peptide.