What role do biomarkers play in clinical trials?

Biomarkers are crucial in clinical trials as they help determine a patient’s response to investigational drugs, improving drug efficacy and minimising side effects. Biomarkers guide patient selection, monitor treatment effectiveness, and support the development of precision medicine by identifying biological indicators linked to disease progression.

How are biomarkers identified in clinical trials?

Biomarkers are identified through various techniques like DNA sequencing, gene expression profiling, and bioanalytical testing. These methods help detect specific biological signals that relate to drug response, safety, or disease status.

What are the benefits of using biomarkers in drug development?

The use of biomarkers accelerates drug development by enabling personalised treatment plans and improving trial success rates. They help in identifying suitable patient populations, reducing trial costs, and increasing the likelihood of regulatory approval by demonstrating clear efficacy and safety profiles.

What services do biomarker companies provide?

Biomarker companies offer services such as biomarker discovery, validation, and clinical assay development. These include technologies like immune monitoring, flow cytometry, and genomics to support clinical trial data analysis and ensure precise results.

How do biomarkers support precision medicine?

Biomarkers allow for the development of precision medicine by identifying individual patient differences in disease mechanisms and drug response. This enables the creation of targeted therapies tailored to specific biological profiles, improving treatment outcomes and reducing adverse effects.