Global clinical trials activity decreased by 7.6% in Q2 2022, when compared with the same quarter in 2021, according to GlobalData.
Industry sponsored trials accounted for a 52.9% share of overall activity in Q2 2022, an increase of 5.5% when compared with Q2 2021.
Non-industry sponsored trials accounted for a 47.1% share of all clinical trials in Q2 2022, marking a decrease of 5.5% when compared with the same period in 2021.
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Q2 2022 industry sponsored clinical trials activity by therapy areas
Oncology was the leading therapy area for industry sponsored clinical trials in Q2 2022, accounting for a 31.7% share of all trials.
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By GlobalDataThis was followed by Central Nervous System with a 14.0% share, Infectious Disease with 13.8%, Cardiovascular with 7.6%, and Metabolic Disorders with 7.4%.
In Q2 2021, Oncology led with a 28.0% share, followed by Infectious Disease with 17.7%, Central Nervous System with 12.9%, Metabolic Disorders with 9.2%, and Cardiovascular with 8.5%.
Industry sponsored trials: Q2 2022 vs Q2 2021 | |||
---|---|---|---|
Therapy Area | Q2 2021 | Q2 2022 | Activity |
Oncology | 28.0% | 31.7% | |
Central Nervous System | 12.9% | 14.0% | |
Infectious Disease | 17.7% | 13.8% | |
Cardiovascular | 8.5% | 7.6% | |
Metabolic Disorders | 9.2% | 7.4% | |
Gastrointestinal | 6.5% | 5.7% | |
Respiratory | 5.5% | 5.2% | |
Dermatology | 4.9% | 4.6% | |
Immunology | 5.1% | 4.6% | |
Musculoskeletal Disorders | 3.7% | 3.5% | |
Hematological Disorders | 2.3% | 3.2% | |
Genito Urinary System And Sex Hormones | 2.9% | 2.7% | |
Ophthalmology | 2.2% | 2.6% | |
Genetic Disorders | 1.6% | 2.5% | |
Ear Nose Throat Disorders | 1.3% | 1.3% | |
Women’s Health | 1.8% | 1.3% | |
Male Health | 1.1% | 0.7% | |
Hormonal Disorders | 0.7% | 0.6% | |
Mouth and Dental Disorders | 0.6% | 0.4% | |
Nutritional Disorders | 0.3% | 0.3% | |
Non Malignant Disorders | 0.1% | 0.2% |
Most active therapy areas in non-industry sponsored clinical trials
In Q2 2022 the leading therapy area for non-industry sponsored clinical trials was Oncology, accounting for a 25.7% share of all trials.
This was followed Central Nervous System with a 25.6% share, Infectious Disease with 11.4%, Cardiovascular with 9.8%, and Metabolic Disorders with 5.9%.
In Q2 2021, Central Nervous System held the lead in non-industry sponsored clinical trials with a 23.0% share, followed by Oncology with 21.8%, Infectious Disease with 17.4%, Cardiovascular with 9.3%, and Gastrointestinal with 6.8%.
Non-Industry sponsored trials: Q2 2022 vs Q2 2021 | |||
---|---|---|---|
Therapy Area | Q2 2021 | Q2 2022 | Activity |
Oncology | 21.8% | 25.7% | |
Central Nervous System | 23.0% | 25.6% | |
Infectious Disease | 17.4% | 11.4% | |
Cardiovascular | 9.3% | 9.8% | |
Metabolic Disorders | 5.6% | 5.9% | |
Gastrointestinal | 6.8% | 5.6% | |
Musculoskeletal Disorders | 4.8% | 5.5% | |
Respiratory | 4.6% | 4.2% | |
Women’s Health | 4.3% | 3.9% | |
Genito Urinary System And Sex Hormones | 3.3% | 2.7% | |
Immunology | 3.4% | 2.7% | |
Dermatology | 2.9% | 2.5% | |
Hematological Disorders | 2.7% | 2.5% | |
Mouth and Dental Disorders | 2.0% | 2.2% | |
Ophthalmology | 1.8% | 1.5% | |
Ear Nose Throat Disorders | 1.2% | 1.3% | |
Genetic Disorders | 0.5% | 1.0% | |
Nutritional Disorders | 0.9% | 0.9% | |
Hormonal Disorders | 0.7% | 0.5% | |
Male Health | 0.4% | 0.5% | |
Non Malignant Disorders | 0.3% | 0.4% |
Asia-Pacific region has the most activity for industry sponsored clinical trials
Asia-Pacific was the most active region for industry sponsored clinical trials activity in Q2 2022 with a 52.6% share, compared with 57.5% in Q2 2021.
North America was the second most active region with a 32.0% share in Q2 2022, up from 30.7% in Q2 2021, followed by Europe with a 28.3% share in Q2 2022, up from 27.2% in Q2 2021.
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Single country studies held an 85.3% share in industry sponsored clinical trials in Q2 2022, compared with 82.7% in Q2 2021. Multinational trials accounted for 14.7% in Q2 2022, against 17.3% in Q2 2021.
Regional activity for non-industry sponsored clinical trials
Asia-Pacific saw the most non-industry sponsored clinical trial activity in Q2 2022 with a 55.5% share, up from 49.6% in Q2 2021.
North America held the second position with a 21.7% share in Q2 2022, compared with 14.3% in Q2 2021. This was followed by Europe with a 14.1% share in Q2 2022, as against 16.5% in Q2 2021.
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Single country studies accounted for 98.7% share of non-industry sponsored clinical trials in Q2 2022, compared with 98.9% in Q2 2021. Multinational trials accounted for a 1.3% share in Q2 2022, up from 1.1% in Q2 2021.
Clinical trials by phase in Q2 2022
Phase II trials outnumbered all other studies with a 37.7% share for industry sponsored trials in Q2 2022, compared with 34.9% in Q2 2021.
The share of Phase I trials stood at 35.8% in Q2 2022, down from 36.2% in Q2 2021. Phase III trials decreased to 16.0% in Q2 2022, compared with 16.1% in Q2 2021, followed by Phase IV trials with a 10.5% share in Q2 2022, against 12.8% in Q2 2021.
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For non-industry sponsored clinical trials, Phase II activity increased to a 48.3% share in Q2 2022, compared with 42.7% in Q2 2021.
Phase IV trials were the second most active with a 21.1% share in Q2 2022, compared with 22.8% in Q2 2021. Phase I trials held a 17.8% share in Q2 2022, against 13.6% in Q2 2021, followed by Phase III trials with a 12.8% share in Q2 2022, over 21.0% in Q2 2021.
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Methodology:
The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.