Italy has accounted for a 3.4% share of the global clinical trials activity in 2021, registering a decrease when compared with the last ten-year average of a 4.6% share, according to GlobalData.

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Industry sponsored trials outnumber non-industry sponsored trials in Italy

Industry sponsored trials held an 81.4% share of all the clinical trials in Italy in 2021, when compared with the ten-year average of 75.3%. Non-industry sponsored trials accounted for an 18.6% share in 2021 as against the average of 24.7% in the last ten years.

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Top therapy areas for industry sponsored clinical trials in Italy

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Oncology was the leading therapy area for industry sponsored clinical trials in Italy in 2021 with a 38.7% share, as against a five-year average of 40.8% and a ten-year average of 39.7%.

Central Nervous System held a 10.4% share in 2021, over a five-year average of 11.4% and a ten-year average of 11.4%.

Infectious Disease held an 8.0% share in 2021, compared to a five-year average of 7.2% and a ten-year average of 8.2%. Immunology held a 7.1% share in 2021, as against a five-year average of 6.1% and a ten-year average of 6.3%.

Gastrointestinal held a 6.7% share, over a five-year average of 6.4% and a ten-year average of 5.7%.

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Top therapy areas for non-industry sponsored clinical trials in Italy

Infectious Disease was the leading therapy area for non-industry sponsored clinical trials in Italy in 2021 with a 25.6% share, as against a five-year average of 11.2% and a ten-year average of 10.9%.

Oncology held a 25.0% share in 2021, over a five-year average of 24.6% and a ten-year average of 30.0%.

Central Nervous System held a 13.8% share in 2021, compared to a five-year average of 18.3% and a ten-year average of 18.2%. Cardiovascular held a 13.1% share in 2021, as against a five-year average of 13.5% and a ten-year average of 16.4%.

Respiratory held an 8.1% share, over a five-year average of 5.8% and a ten-year average of 5.5%.

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Phase III trials lead industry sponsored clinical trials in Italy in 2021

Phase III trials held a 44.7% share of industry sponsored clinical trials in Italy in 2021, over a five-year average of 46.4% and a ten-year average of 46.6%.

Phase II trials held a 41.3% share in 2021, as against a five-year average of 39.1% and a ten-year average of 37.4%. Phase IV trials held a 9.8% share in 2021, compared to a five-year average of 9.5% and a ten-year average of 11.3%.

Phase I trials held a 4.1% share in 2021, over a five-year average of 5.1% and a ten-year average of 4.7%.

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Phase II trials lead non-industry sponsored clinical trials in Italy in 2021

Phase II trials held a 55.0% share of non-industry sponsored clinical trials in Italy in 2021, over a five-year average of 55.4% and a ten-year average of 52.1%.

Phase IV trials held a 25.0% share in 2021, as against a five-year average of 28.6% and a ten-year average of 30.6%. Phase III trials held a 17.5% share, compared to a five-year average of 14.3% and a ten-year average of 15.4%.

Phase I held a 2.5% share in 2021, over a five-year average of 1.7% and a ten-year average of 2.0%.

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Methodology:

The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.