Japan has accounted for a 4.7% share of the global clinical trials activity in 2022, registering a decrease when compared with the last ten-year average of an 8.9% share, according to GlobalData.

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Industry sponsored trials outnumber non-industry sponsored trials in Japan

Industry sponsored trials held a 54.0% share of all the clinical trials in Japan in 2022, when compared with the ten-year average of 54.0%. Non-industry sponsored trials accounted for a 46.0% share in 2022 as against the average of 46.0% in the last ten years.

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Top therapy areas for industry sponsored clinical trials in Japan

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Oncology was the leading therapy area for industry sponsored clinical trials in Japan in 2022 with a 25.1% share, as against a five-year average of 31.7% and a ten-year average of 29.4%.

Central Nervous System held a 15.2% share in 2022, over a five-year average of 12.1% and a ten-year average of 12.1%.

Immunology held an 8.1% share in 2022, compared to a five-year average of 6.5% and a ten-year average of 6.5%. Metabolic Disorders held an 8.0% share in 2022, as against a five-year average of 8.2% and a ten-year average of 10.8%.

Infectious Disease held a 7.0% share, over a five-year average of 7.1% and a ten-year average of 7.1%.

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Top therapy areas for non-industry sponsored clinical trials in Japan

Oncology was the leading therapy area for non-industry sponsored clinical trials in Japan in 2022 with a 31.0% share, as against a five-year average of 33.7% and a ten-year average of 34.7%.

Central Nervous System held a 12.6% share in 2022, over a five-year average of 13.9% and a ten-year average of 12.7%.

Gastrointestinal held an 11.0% share in 2022, compared to a five-year average of 10.0% and a ten-year average of 10.2%. Cardiovascular held a 10.1% share in 2022, as against a five-year average of 10.2% and a ten-year average of 10.6%.

Metabolic Disorders held an 8.9% share, over a five-year average of 8.3% and a ten-year average of 9.9%.

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Phase II trials lead industry sponsored clinical trials in Japan in 2022

Phase II trials held a 35.7% share of industry sponsored clinical trials in Japan in 2022, over a five-year average of 39.2% and a ten-year average of 38.4%.

Phase III trials held a 33.2% share in 2022, as against a five-year average of 30.4% and a ten-year average of 31.1%. Phase I trials held a 17.4% share in 2022, compared to a five-year average of 15.1% and a ten-year average of 15.2%.

Phase IV trials held a 13.7% share in 2022, over a five-year average of 15.3% and a ten-year average of 15.3%.

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Phase II trials lead non-industry sponsored clinical trials in Japan in 2022

Phase II trials held a 62.0% share of non-industry sponsored clinical trials in Japan in 2022, over a five-year average of 70.2% and a ten-year average of 72.5%.

Phase IV trials held a 19.6% share in 2022, as against a five-year average of 15.8% and a ten-year average of 13.8%. Phase I trials held an 11.7% share, compared to a five-year average of 6.4% and a ten-year average of 7.5%.

Phase III held a 6.7% share in 2022, over a five-year average of 7.7% and a ten-year average of 6.2%.

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Methodology:

The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.