The funding claims to strengthen the capabilities of the research sector. Credit: © Commonwealth of Australia | Department of Health and Aged Care.

The Australian Government’s Department of Health and Aged Care has announced the ‘2024 Clinical Trial Enabling Infrastructure’ grant opportunity, offering A$35.7m ($22.1m) for ‘innovation’ projects and medical research.

As part of the Medical Research Future Fund’s (MRFF) National Critical Research Infrastructure initiative, the funding claims to address ‘unmet’ medical needs via registry-based randomised controlled trials or adaptive platform trials.

The projects will strengthen the capabilities and collaboration of the research sector through new or expanded trial practice networks.

Applications for the grant are set to open on 13 February, with the MRFF’s National Critical Research Infrastructure initiative set to invest A$600m over ten years, from 2024–2025.

The main objective of the initiative is to establish and extend critical research infrastructure, including equipment, facilities, services, and systems to conduct medical research.

It is overseen by the Health and Medical Research Office and other MRFF initiatives, and administered by the Department of Industry, Science and Resources.

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The initiative claims to increase the country’s capacity to conduct health and medical research and the funding will be provided through the innovation enablers, digitisation of healthcare, co-investment partnerships, and mRNA technology enablers streams.

Stream one is set to ‘promote’ the development of novel research infrastructure to address unmet medical needs, including biobanks and secure health data environments.

The second stream aims to advance digital healthcare solutions such as AI-enabled health interventions.

Stream three will leverage co-investments for significant critical research infrastructure projects. Finally, stream four will focus on enhancing mRNA technology for vaccine and therapeutic development in areas of unmet medical need.

An A$22bn long-term investment established by the Australian Government in 2015, the MRFF has grown to its current size as of December 2023.