The study will assess the vaccine candidate’s safety and ability to induce an immune response. Credit: University of Oxford.

Brazil’s health regulator Anvisa has approved clinical trials of a Covid-19 vaccine candidate developed by researchers at University of Oxford in the UK and supported by AstraZeneca.

The Phase III trial will assess the safety and efficacy of the vaccine candidate, ChAdOx1 nCoV-19.

Go deeper with GlobalData

Data Insights

The gold standard of business intelligence.

Find out more

Related Company Profiles

View all

The Federal University of Sao Paulo (Unifesp) will help conduct the study, which is set to begin this month and enrol 2,000 participants. Unifesp intends to enrol 1,000 front-line Covid-19 volunteers who have not been infected.

Anvisa was quoted by Reuters as saying: “This is a randomised controlled phase III study to determine the safety, efficacy … of the non-replicating ChAdOx1 nCoV-19 vaccine.

“Initial non-clinical studies in animals and Phase I clinical studies in humans to evaluate the safety of the vaccine were carried out in England and the results demonstrated that its safety profile was acceptable.”

Developed by Jenner Institute and Oxford Vaccine Group at Oxford University, the Covid-19 vaccine candidate is based on an adenovirus vaccine vector and the SARS-CoV-2 spike protein.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

Upon vaccination, the surface spike protein is generated, which induces the immune system to attack SARS-CoV-2 if the virus later infects the body.

The university started enrolment of healthy volunteers for a clinical trial of the vaccine in the UK in March this year. The trial is designed to enrol up to 510 participants aged 18 to 55 years.

During the study, the vaccine candidate’s safety and ability to induce an immune response will be assessed. Results from the trial are expected next month, with plans to start late-stage trials by the middle of this year.

AstraZeneca signed an agreement with the university in April to develop and distribute the vaccine candidate.

As part of the agreement, AstraZeneca will carry out the development and global manufacturing and distribution of the Covid-19 vaccine.