Vanda Pharmaceuticals has reported data from a Phase II clinical trial of VQW-765 for the treatment of acute performance anxiety.
The placebo-controlled, randomised, multicentre, double-blind study (Study 2201) has been designed for assessing VQW-765’s efficacy and safety in performance anxiety patients.
Go deeper with GlobalData
In the study, 230 participants with previous performance anxiety history were randomised and given a single VQW-765 dose or a placebo and challenged with the standardised Trier Social Stress Test (TSST).
The TSST induces stress by requiring participants to make an interview-style presentation before an interview panel.
Findings showed that the participants who were given VQW-765 demonstrated less stress levels compared to the placebo-treated group.
The company stated that specifically female participants of the trial, nearly 70% of the total participants, had statistically significant responses to VQW-765.
How well do you really know your competitors?
Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.
Thank you!
Your download email will arrive shortly
Not ready to buy yet? Download a free sample
We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form
By GlobalDataThey reported a higher stress reaction, as well as a higher prevalence of performance anxiety, as compared to male participants.
Vanda noted that a significant relationship was also observed between exposure to VQW-765 and the clinical response.
A new small molecule alpha 7 nicotinic acetylcholine receptor (α7-nAChR) partial agonist, VQW-765 binds and improves the activity of one type of nicotinic receptor that is composed of a pentameric assembly of the alpha 7 subtype.
The company claimed that VQW-765 is first that has shown efficacy in a clinical study of performance anxiety.
It also noted that the significant relationship between the exposure and clinical outcome observed in the Study 2201 further supports the hypothesis that the therapy may be effective for the treatment of performance anxiety.
