Reviving small molecules in the Alzheimer’s pharmaceutical race
The complexity of Alzheimer’s pathogenesis means that treating the disease is a high stakes game of whack-a-mole.
02 January 2024
02 January 2024
The complexity of Alzheimer’s pathogenesis means that treating the disease is a high stakes game of whack-a-mole.
In a previous Phase II trial, mazdutide was found to be well-tolerated with no new safety concerns reported.
The South Korean company plans to use the funds to advance the development of endometriosis therapy, merigolix.
Although the clinical trial landscape has had a rocky few years, 2023 has seen a number of innovative new drugs make it to market.
The trial has so far enrolled 290 subjects across trial sites in Asia, Europe and Latin America.
Jiangsu Recbio Technology will also run a Phase I trial in 180 healthy adult subjects aged 40 yea and above in China.
The regulatory development comes after a case of serious adverse event was reported in the trial.
Evaluating the tolerability and safety of DA-1726 will be the primary endpoint of the trial.
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