Portable Transmission Raman Spectroscopy

By B&W Tek

Content uniformity (CU) testing is a crucial task in pharmaceutical manufacturing, as it ensures that each product that reaches a consumer contains a safe dosage of the active pharmaceutical ingredient (API). Traditionally, high-performance liquid chromatography (HPLC) was performed off-line in a quality control lab to monitor the dosage of finished tablets due to its sensitivity and the ability to obtain a measurement from the entire volume of the tablet. However, HPLC analysis involves a large amount of solvent and consumables, and often takes hours to complete. This slow and destructive technique requires highly trained personnel and can cause delays in the manufacturing process.

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